Food Processing: Techniques and Technology Food Processing: Techniques and Technology Техника и технология пищевых производств 2074-9414 2313-1748 119335 10.21603/2074-9414-2026-1-2631 MEXSTP ОРИГИНАЛЬНАЯ СТАТЬЯ ORIGINAL ARTICLE ОРИГИНАЛЬНАЯ СТАТЬЯ Effect of Acidic Media on Folic Acid Solubilization Patterns Исследование влияния некоторых кислот на процесс растворимости фолиевой кислоты Лобзанова Марина Евгеньевна Lobzanova Marina E. https://orcid.org/0000-0003-3214-8889 Сухих Андрей Сергеевич Sukhikh Andrey S. https://orcid.org/0000-0001-7035-673X Альтшулер Ольга Генриховна Altshuler Olga G. https://orcid.org/0000-0002-1252-9572 Иванова Светлана Анатольевна Ivanova Svetlana A. pavvm2000@mail.ru

доктор технических наук;

doctor of technical sciences;

 Кемеровский государственный университет Кемерово Россия Kemerovo State University Kemerovo Russian Federation Кемеровский государственный университет Кемерово Россия Kemerovo State University Kemerovo Russian Federation Кемеровский государственный университет Кемерово Россия Kemerovo State University Kemerovo Russian Federation Кемеровский государственный университет Россия Kemerovo State University Russian Federation 31 03 2026 31 03 2026 56 1 154 163 15 12 2025 03 03 2026 https://fptt.ru/en/issues/24227/24277/

В современном мире проблема дефицита микронутриентов остается актуальной для населения разных стран мира. Одним из эффективных решений является обогащение пищевых продуктов витаминами и минералами. Фолиевая кислота (витамин B9) играет ключевую роль в профилактике различных заболеваний, включая дефекты нервной трубки у новорожденных. Однако эффективность обогащения продуктов напрямую зависит от биодоступности и растворимости вносимого компонента. Цель исследования – изучить влияние свойств водных растворов некоторых кислот на растворимость фолиевой кислоты как фактор ее биодоступности. Объекты исследования – фолиевая кислота и ее растворы в воде, содержащей лимонную, аскорбиновую, янтарную и солюбилизированную аминоуксусную кислоты разной концентрации (3, 5 и 10 %). Для оценки растворимости фолиевой кислоты в растворах использовали УФ-спектроскопию и ВЭЖХ. Полученные данные обрабатывали статистическими методами. Проведенный анализ показал значительное влияние среды на растворимость фолиевой кислоты. Исследование подтвердило, что выбор среды растворения критически важен для повышения биодоступности фолиевой кислоты при обогащении пищевых продуктов. При изучении влияния растворов кислот на растворимость фолиевой кислоты в стандартных условиях установлено, что наибольшим потенциалом обладал 10 % водный раствор солюбилизированной аминоуксусной кислоты (глицина). В исследовании этому раствору соответствовала наибольшая интенсивность поглощения фолиевой кислоты, превосходящая значения, соответствующие ее водному раствору, и наибольшая степень высвобождения фолиевой кислоты. Характер кривых поглощения указывал на равномерное распределение молекул в растворе и стабильность растворенной формы. Полученные результаты могут быть использованы для оптимизации технологий обогащения продуктов питания фолиевой кислотой, что позволит повысить эффективность профилактики фолиеводефицитных состояний среди населения.

Availability of micronutrients remains a major global concern. Fortified foods are inherently rich in vitamins and minerals; for instance, folic acid, or vitamin B9, is essential for preventing such health issues as neural tube defects in newborns. However, the efficacy of functional food depends on the bioavailability and solubility of the fortifying nutrients. This study focused on the solubility folic acid in aqueous solutions with citric, ascorbic, and succinic acids at various concentrations (3, 5, and 10%). The methods of UV spectroscopy and high-performance liquid chromatography (HPLC) were employed to analyze the solubility of folic acid, with the resulting data processed using standard statistical methods. The dissolution medium had a reliable impact on the solubility of folic acid. Selecting an appropriate dissolution medium proved crucial for enhancing the bioavailability of folic acid in food fortification. The 10% aqueous solution of aminoacetic acid (glycine) demonstrated the greatest potential under standard conditions. This solution achieved the highest levels of folic acid absorption and release, surpassing those for the aqueous solution of folic acid. The absorption curves suggested a uniform molecular distribution within the solution, as well as the stability of the dissolved form. The results can be used to optimize existing food fortification technologies, thereby helping to prevent folic acid deficiency.

 Фолиевая кислота микронутриенты водный раствор кислоты глицин растворимость УФ-спектроскопия Folic acid micronutrients aqueous acid solution glycine solubility UV spectroscopy

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