<p>The article features a study of the peculiarities of heart rate regulation in 46 students in 2 stages of training: the beginning and the end of the academic year. The indices of variation pulsometry were analyzed at rest and in orthostasis, taking into account the type of daily activity. The data analysis has revealed signs of the extinction of the structural trace of longterm adaptation to the learning process in the group during the summer period. It is shown that in the end of academic year, compared with the autumn period, students demonstrate a decrease in sympathetic activity of the nervous system at rest, and the stress response to the study load is more pronounced. It was found out that those students who were examined in the autumn period formed a stable mechanism of vegetative regulation to educational activity and took place at the expense of the lower links of nervous and humoral regulation, with a higher level of functional reserves involved in the formation of successful adaptation to the academic process. It has been revealed that students with different types of daily activity demonstrate adaptation processes with their own specifi at the beginning and the end of the academic year: in individuals with an evening type in the summer period, sympathetic infl were predominantly determined by the central mechanisms of the regulation of the sympathetic adrenal system.</p>